Taking on the immense hate there is out there for gay and transgender people is a very, very difficult thing to do. You open yourself up to all sorts of attack, both verbally and physically - in the online world and also in the real world.
In the past few years I have built up a small collection of what I call "fan mail" from "admirers" who have threatened - even from half the world away - to hurt me and even to kill me. Some of the lesser creative ones have even threatened legal action without any solid basis whatever for daring to tackle their unadulterated bigotry. Some of them would make pretty good one-liners, except they have no actual punchline. Just to cheer me up, I have also committed to memory the verbal threats and bullying I have been faced with in real life.